PAVEX PLUS
PARVAQUONE AND FUROSEMIDE INJECTION
PAVEX PLUS is a potent injection treatment for theileriosis (East Coast Fever, ECF), particularly for advanced cases with pulmonary oedema. Parvaquone is theilericidal, acting on schizonts and piroplasms; Furosemide is a diuretic, which resolves pulmonary oedema.
Category
Veterinary Medicines, Liquid Injections
Pack Size
50 ml, 100 ml
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Contact supportCOMPOSITION
Each ml contains :
Parvaquone
150 mg
Furosemide
B.P. 55 mg
Sorbitan mono oleate (as preservative)
B.P. 100 mg
Oily base
q.s.
INDICATION
A potent injection treatment for theileriosis (East Coast Fever, ECF), particularly for advanced cases with pulmonary oedema. Parvaquone is theilericidal, acting on schizonts and piroplasms; Furosemide is a diuretic, which resolves pulmonary oedema.
CONTRAINDICATIONS AND WARNINGS
East Coast Fever (ECF) is an immuno depressive disease and potentially fatal concurrent infections are common. In particular, anaplasmosis may be activated from the carrier state and the principal lesions of ECF, such as oedema of the lungs and the alimentary canal, predispose to bacterial pneumonia and enteritis. The symptoms of these conditions may be masked by those of ECF. Special care should be taken to diagnose any complicating conditions and to treat them promptly and specifically.
Adverse reaction to Parvaquone is extremely rare. Furosemide is chemically similar to the sulphonamides so Pavex Plus should not be used in animals with sulphonamide sensitivity.
Local swelling may occur at the injection site but this is usually transient.
DOSAGE AND ADMINISTRATION
Inject by the Intramuscular route into the neck muscles at the rate of 1 ml/15 kg (10.0 mg Parvaquone, 3.6 mg Furosemide per kg). Repeat after 48 hours. In cases of exceptionally severe infections with pulmonary oedema, further treatment at half the dosage rate may be required at 24 hour intervals.
| SPECIES | DOSE |
|---|---|
| Calves | 1 ml per 15 kg bodyweight. |
| BODYWEIGHT | DOSE |
| 100 kg | 7 ml |
| 150 kg | 10 ml |
| 200 kg | 14 ml |
| 200 kg | 17 ml |
| 300 kg | 20 ml |
Alternatively, when pulmonary symptoms have been resolved by Pavex Plus, treatment to achieve parasitic cure may be completed with Pavex, which contains only Parvaquone, at a dose rate of 1 ml/15 kg every 48 hours. Do not use by the Intravenous or Subcutaneous routes. Normal aseptic precautions should be observed.
WITHDRAWAL PERIOD
| TYPE/SPECIES | PERIOD |
|---|---|
| Milk | 14 days |
| Meat | 28 days |