FLUXANE
FLUNIXIN MEGLUMINE INJECTION USP 5% W/V
Fluxane is use for the control of pyrexia and inflammation in Cattle and alleviation of inflammation and pain in Horses.
Category
Veterinary Medicines, Liquid Injections
Pack Size
20 ml, 50 ml, 100 ml
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Contact supportCOMPOSITION
Each ml contains :
Flunixin meglumine
USP
equi. to Flunixin
50 mg
Phenol
B.P. 0.5% w/v
Water for Injection
B.P. q.s.
INDICATION
Cattle : For the control of pyrexia and inflammation associated with mastitis, respiratory tract infection & endotoxemia. For the treatment of pain and inflammation associated with musculoskeletal disorders.
Horses : For the alleviation of inflammation and pain associated with musculoskeletal disorders. It is recommended for the alleviation of visceral pain associated with colic.
SIDE EFFECTS
Untoward effects include gastrointestinal irritation, ulceration, changes in haematology and, in dehydrated, hypovolaemic or hypotensive animals, a potential for renal damage. In rare cases, severe anaphylactoid reactions have been observed, occasionally with fatal outcome.
CONTRAINDICATIONS
Do not exceed the recommended dose or duration of treatment. Do not use in Horses used in competitive sports. Do not administer to pregnant mares, or 48 hours before expected parturition until postpartum expulsion of the placenta in Cows.
Do not use in lactating mares producing milk for human consumption.
Do not use in Bulls intended for breeding, as reproductive effects of Fluxane in these classes of Cattle have not been investigated.
Do not administer to animals suffering from cardiac, hepatic or renal disease.
Fluxane is contraindicated in animals with risk of gastrointestinal ulceration or bleeding, where there is evidence of a blood dyscrasia or hypersensitivity to the product. Do not administer to animals undergoing general anaesthesia until fully
recovered. Avoid intra-arterial injection or concurrent administration of other NSAIDs and nephrotoxic drugs. Use in any animal less than 6 weeks of age or in aged animals may involve additional risks.
DOSAGE AND ADMINISTRATION
| SPECIES | DOSE |
|---|---|
| Cattle | The recommended dose is 2.2 mg/kg (2 ml/45 kg) body weight for the antipyretic effect in acute inflammatory conditions in Cattle. Intravenous administration is recommended. The cause of the acute inflammatory condition should be determined and appropriate concomitant therapy initiated. |
| Horses | The recommended dose for musculoskeletal disorders in Horses is 1.1 mg per kg (1 ml/45 kg) of body weight once daily. Treatment may be given by Intravenous or Intramuscular injection and repeated for up to five days. |
Studies show that onset of activity is within two hours. Peak response occurs between 12 and 16 hours and duration of activity is 24-36 hours. The recommended dose for the alleviation of pain associated with equine colic is 1.1 mg per kg of body weight. Intravenous administration is recommended for prompt relief. Clinical studies show pain is alleviated in less than 15 minutes in many cases. Treatment may be repeated when signs of colic recur. During clinical studies approximately 10% of the Horses required one or two additional treatments. The cause of colic should be determined and treated with concomitant therapy.
WITHDRAWAL PERIOD
| TYPE/SPECIES | PERIOD |
|---|---|
| IV | Meat and offals : 5 days, Milk : 72 hours |
| IM or SC | Meat and offals : 31 days, Milk : 120 hours |